We are very Pro-Natural-Vitamin-D! But please see caution on synthetic-soy-vitamin-D and long-term high-dosing below. The goitrogens in processed modern soy are anti-thyroid. Soy = Low Thyroid Function = Low Metabolism = Low Energy.
Morley Robbins and Anna from 4Health by Anna Sparre:
or use alternative audio here.
The medical research literature shows a rather amazing metabolic cascade for maintaining bone strength and building new bone:
Iron is the only element on this planet that causes calcium loss in hard tissue and it goes on to cause calcium buildup in the soft tissue. ~ Morley Robbins.
2.) Magnesium regulates calcium absorption and active vitamin D (hormone-D).
3.) Iron build up in the bone marrow prevents new bone building.
4.) Magnesium and bioavailable copper (ceruloplasmin) activate bone building (and prevent excess iron build up.)
5.) Biological transmutation from silica to calcium. (below)
Iron causes calcium to leave bone tissue and move into soft connective tissue (such as cartilage) causing calcification.
Iron is the only element on this planet that causes calcium loss in hard tissue and it goes on to cause calcium buildup in the soft tissue. ~ Morley Robbins, 49:30 minutes, Morley Robbins and Anna Sparre 4Health (#218b)
So it turns out that iron is in fact the cause of the actual breakdown of the bone tissue or bone matrix, allowing the release of calcium into the bloodstream. Taking calcium is not going to reverse that problem! ~ Morley Robbins
It may be necessary to supplement HIGH DOSE Vit D temporarily as explained on this audio discussion. But understanding Vit D - magnesium metabolism is important for long term health. Listen to this essential audio.
Dr. Ben Edwards and Morley Robbins, June 3, 2021 Let's Drill into Hormone D
[25:00 minutes] Low vitamin D status (Vitamin 25 D3 - the storage form called calcidiol) is an indication of low magnesium. [24:00 minutes] Magnesium is required to convert storage-D to active-D. Human biology has an elegant conversion system. Vit D3 is converted to storage-D3. Storage-D3 is converted to active-D3. The technical terms are: D3-cholecalciferol to 25 D3-calcidiol to 1/25 D3-dihydroxy-cholecalciferol.
It's the iron complexities again: [25:00 minutes]
What are the metabolic requirements for inflammation? You have to have a lot of iron and a little bit of magnesium...you then will have inflammation. That is a proven metabolic fact....low mag = high inflammation. Low mag also = low vit D because the enzyme does not work right....[15:00 minutes] and high iron and low magnesium in the liver will block the enzyme function to create storage-D. [Storage-D] is low for metabolic reasons not because it is empty.
[20:00 minutes Drill into Hormone D] Vitamin-hormone D is a powerful temporary anti-inflammatory, suppressing a hyper-immune response similar to steroid action. [20 minutes]
This can be life-saving when your [immune system] is really inflamed. So, supplementing HIGH DOSE Vit D can be a TEMPORARY help to suppress the hyper-inflammatory response of an overactive immune system. I.e. not a life-long supplementation. For many people it is the conversion from storage-D to active-D which needs to take place to make vit D effective. Vit D activation and de-activation are magnesium dependent. In the long run, it is essential to restore magnesium balance and reduce iron overload. Long-term, high dose vit D can have unitended consequences (similar to long-term steroid use) causing metabolic chaos.
Two of the metabolic chaos concerns with long-term high dose vitamin D supplementation are that vitamin D blocks vitamin A (retinol) and renal potassium wasting. More details on the audio.
Please be cautious with SYNTHETIC Soy-Based (lab-synthesized-soy-based) supplementation. Why? There are just a lot of unanswered questions on how the synthetic, soy-based supplements work.
There are vitamin D supplements emulsified in natural oils, such as sunflower oil, that can be used temporarily with less concern for the goitrogenic side effects associated with processed soy.
Try cod liver oil, black seed oil (black cumin oil), dairy (butter), sheep's wool, Mushrooms:
The most vitamin D was found in shiitake dried with gills up that were exposed to sunlight for two days, six hours per day... and more! Also, increasing your magnesium and vitamin A (retinol) levels will help your body generate vitamin D.
Vitamin D has multiple metabolic pathways. We typically measure just one pathway in the blood, not in the liver or any other storage areas. Likewise, there are over 5 different types of vitamin D and again, we are measuring just one.
Vitamin D Researcher Jim Stephenson Jr gives an in-depth review:
The main vitamin D3 molecule is cholecalciferol. The storage form of vitamin D3 is 25 D Calcidiol. 25 D Calcidiol (storage D) is most often used to measure vitamin D status. The research abbreviation for 25 D Calcidiol is [25(OH)D3]. The ACTIVE form of vitamin D3 is 1/25 D-dihydroxy-cholecalciferol. 1/25-D-dihydroxy-cholecalciferol (active D) has a diurnal rhythm and is made daily.
The Vitamin D family includes D1, D2, D3, D4, D5 and more: Vitamin D1-ergocalciferol / lumisterol,Vitamin D2-ergocalciferol (three types), vitamin D3-cholecalciferol (three types), vitamin D4-22-dihydroergocalciferol, vitamin D5-sitocalciferol...there are more.
As you research vitamin D, here are some additional concerns. Vitamin D prevents retinol (Vit A) absorption and retinol is absolutely essential for healthy liver function. Vitamin D3 (cholecalciferol) is a main ingredient in rat poison. Large doses of fish oil can act as a blood thinner to prevent blood clot formation. Why is Vitamin D so heavily promoted? One reason is mega-money synthetic vitamin D3 patents by big corporations. There are significant amounts of contradictory research data on high dose supplementation. Who paid for which research? Why the contradiction and which data is correct?
A lot of lab research manipulates complex biological pathways resulting in unintended consequences instead of observing how the healthy human body is managing and maintaining itself.
For those interested in additional information. Lots of details. Additional Vitamin-Hormone D complexities. Listen to a very detailed discussion on how magnesium activates and regulates vitamin D pathways in the human bio system. Dr. Wade Anunsen on Frankly Speaking interviews Morley Robbins:
Why is everyone Vit D deficient?
Alt Link: Youtube
Also see: Morley speaks with Dr Ben Edwards about Hormone D.
More at TheRootCauseProtocol Video Index
The body maintains an intricate and delicate balance between major metabolites. Here are some additional details on the metabolic chaos that may be connected with long-term high dose vitamin D supplementation.
...the intake of that supplement [synthetic vitamin D3] causes potassium wasting...and that's a very scary thing... This puts an extra burden on the body to try to keep equilibrium (homeostatis) despite a loss in potassium, a major metabolite. ~ Morley Robbins
...when someone is sucking down 5000 I.U.'s of [synthetic] vitamin D3 with no regard for retinol (vitamin A) what they don't know is that it's blocking the absorption of retinol and it's causing the loss of retinol that is being stored in the liver and in the eyes....the [vit A/vit D] see-saw is being violated horrifically by synthetic, soy-based, supplemental [vitamin] D... ~ Morley Robbins (Audio Below)
The solution is to self-educate and then stop the loss of bone matrix by rebalancing your magnesium-copper-iron metabolism. How do I start?
Morley Robbins and Anna from 4Health by Anna Sparre (#219b - Vitamin D). Morley is a guest on Anna Sparre's 4Health podcast:
or use alternative audio here.
[5:00 minutes] ...everything about [synthetic] vitamin D supplementation is a lie....What is low vitamin D status? It is actually an indication of magnesium deficiency, not vitamin D deficiency.
[8:30 minutes] ...the intake of that supplement [SYNTHETIC vitamin D] causes potassium wasting. I can look on a hair test and in a nano second I can tell if someone has been taking vitamin D because the potassium has crashed...
[9:20 minutes] ....there is a very important balancing act with vitamin A...nothing in nature exists in isolation...there is balance everywhere in nature. The richest sources of vitamin A and vitamin D are found in cod liver oil... and the ratio is 10 parts retinol (vitamin A) to 1 part vitamin D. Do you think mother nature did that for a reason?...
[23:15 minutes] ...calcium is very important, obviously for our bone structure...and other key metabolic funtions. But we just need a really tiny amount. Especially inside the cell. We need way more magnesium than calcium.
And what mother nature designed was a metabolism that was run by magnesium to regulate the three calciotropic hormones; calcitonin, parathyroid hormone (PTH) and hormone D (active vitamin D). And magnesium status determines how functional and viable those three calciotropic hormones are. And that's not my idea. That is the work of Robert K. Rude, M.D., Ph.D. at the Univeristy of California Medical Center outside of Los Angeles.
So, again, I hope people understand, I have citations to back up all of my positions. And not just average. Robert K. Rude is a demi-god in the world of calcium metabolism and magnesium metabolism....[we need to understand] how powerful that hormone [active vitamin D] is to dictate how much calcium is absorbed in the intestine at the expense of magnesium absorption, I might add.
And that calcium, when it gets into the bloodstream, is not your friend. There is a very tight regulation of the calcium that is in the plasma of the blood... ~ Morley Robbins
There is much more on the podcast.
Morley Robbins and Anna from 4Health by Anna Sparre (#218 - Magnesium). Calcium magnesium metabolic analysis starts at 49:30 minutes:
or use alternative audio here.
So it turns out that iron is in fact the cause of the actual breakdown of the bone tissue or bone matrix, allowing the release of calcium into the bloodstream.
Getting Off The Ferrous Wheel with Morley Robbins (Iron vs. Copper in the body) Episode #159 with Darren McDuffie Morley Robbins
[2:50 minutes] ...We have become iron men and iron women...What I mean by that is that we have become infatuated with iron in this society. A lot of our foods are fortified with iron...I did a blog post many years ago on cereal. What i exposed on that blog post is that when cereal is fortified with iron, they are actually using iron filings...The fact that we are being exposed and over-exposed to iron all the time means it can become toxic within the body.
[53:10 minutes]...What a lot of women worry about as they get older is osteoporosis...And again, what's been drilled into our heads is that you are losing calcium. You need to take calcium to correct that.
Well, the first half of the statement is correct - they are losing calcium. But then you have to ask why they are losing calcium?
It turns out that as the iron builds up in the bone marrow it has an effect on the cells that are designed to make new bone cells...So we have two critical [types] of cells. We have osteoBlasts with a B that are building. And then you have osteoClasts with a C that are crushing or tearing down the bone matrix.
Well, it turns out that the osteoblasts with a B require an enzyme called alkalinphosphotase and also requires lysoxidase in order to make new bone tissue. So you need magnesium for alkalinphosphotase and you need bioavailable copper for the lysoxidase. Well the other side of the story is that there is an enzyme called acidphosphotase and that's the medium of the osteoclasts with a C, that breaks down the [bone] tissue, and it's activated by iron.
So it turns out that iron is in fact the cause of the actual breakdown of the bone tissue or bone matrix, allowing the release of calcium into the bloodstream. Taking calcium is not going to reverse that problem! It has nothing to do with the problem. Taking vitamin D is going to do nothing to reverse that problem. The problem is that there is too much unbound iron in the bone that needs to be offset with bioavailable copper. ~ Morley Robbins
There is much more on the podcast.
Vitamin A is also named Retinol because of it's importance in retina (eye) formation and function.
Morley Robbins with Dr. Jason Dean DC on Retinol and Gut, Vitamin A
The following quotes are from Diatomaceous.org
First off, it's really important to learn about biological transmutation. This is a term that Professor Kervran came up with in 1966 when he published his book... He lived in a part of the country that had no limestone, no calcium in the soil really, and very high in slate, flint stone and mica. These are high silica elements.....
... He observed the chickens in the yard and how they pecked incessantly at mica. He observed how they laid eggs with shells of solid calcium. He observed when his mother cut open the chickens and cut open the gizzard that there was just silica sand left behind. There was this sand left behind from the mica, but the silica aspect was gone....He was determined to figure out being how chickens had solid, hard shells made of calcium, yet when he took the silica out of its diet, the shells were soft, they didn't work and didn't form solid, hard calcium shells...
...The neat thing about Professor Kervran's work is that he proved those 14 atoms of silica and 6 atoms of carbon makes 20 atoms of calcium, and he took these chickens, he gave them no calcium and watched then grows solid, hard calcium eggshells. When he took the silica out of their diet, the eggshells would not even become solid. They were soft and couldn't form the calcium. He's got the equation down, the science on how life, the source element silica, creates calcium and creates the other nutrients and creates the most readily usable form of calcium. We still need some calcium from our outside diet.... ~ Diatomaceous.org